|Test Details||Detection of antigen in postmortem, formalin fixed and paraffin embedded brain tissue|
|Components||Clone AT8 (p-Ser202) performed as an LDT on Ventana Ultra platform|
|Performed||Monday – Friday|
|Turnaround||2 – 3 business days|
|Specimen requirements||FFPE postmortem brain tissue|
Minimum specimen requirement: 2 slides.
If requesting interpretation, please submit an H&E slide.
|Sample collection||Testing currently limited to WU autopsy cases|
|Unacceptable Conditions||Melted block; brain tissue pre-treated with formic acid|
|Miscellaneous||The test was developed by AMP Core Labs in collaboration with the Division of Neuropathology, WU Department of Pathology and Immunology. The tests were validated for use on formalin-fixed postmortem brain tissues; potential effects of formic acid treatment have not been evaluated. The tests are performed using a polymer-based detection system and instrumentation by Ventana Medical Systems. Additional details regarding the procedures are available on request. Results must be interpreted in conjunction with available clinical and pathologic information.|