CKS1B/CDKN2C _ 1p32.3/1q21 | FISH

Test Details Detects amplification or deletion at 1p32.3 and 1q21
Relevant condition(s) Multiple myeloma
Methodology Fluorescence in-situ hybridization
Performed Monday – Saturday
Turnaround 3 – 5 days; STAT FISH performed within 24 – 48 hours
Specimen requirements Suspension FISH on Bone marrow, Bone core, Lymph node or Peripheral Blood ONLY
Sample collection In sterile 15 mL sodium heparin (green-top) vacutainer tube collect 1 – 2 mLs bone marrow; 5 – 10 mLs blood; 0.5 – 1.0 cm2 biopsy (bone core; lymph node); invert tube immediately after collection to prevent clots
Minimum sample volume 0.5 mLs bone marrow; 2 mLs blood
Storage/Transport Conditions Room temperature
Unacceptable Conditions Frozen specimens, clotted or hemolyzed specimens, inappropriate tube type, paraffin sample; Will not be accepted after three days
Special Instructions
CPT Code(s) 88291×1, 88237×1, 88271x 2, 88275×1