Test DetailsChromoSeq™ is a whole genome sequencing assay intended for the comprehensive clinical genomic evaluation of known or suspected hematologic neoplasms including AML and MDS. ChromoSeq™ is capable of unbiased detection of chromosomal translocations, copy number alterations, single nucleotide variants, and insertions/deletions from DNA. The assay can also provide data in the setting of failed or incomplete cytogenetics.
Relevant Condition(s)Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)
MethodologyWhole Genome Sequencing
FrequencyBatched bi-weekly
Turnaround TimeApproximately 21 business days
Specimen Requirements1.0 mL Peripheral Blood or Bone Marrow Aspirate collected within 14 days
Specimen CollectionK2 EDTA vacutainer
Minimum Specimen Volume0.5 mL Peripheral Blood or Bone Marrow Aspirate
Storage/Transport ConditionsShip at room temperature within 72 hours of collection
Unacceptable ConditionsFresh or FFPE tissue, incorrect specimen container, or unlabeled specimen
CPT Code(s)81479