Ambiguous neoplasms: diagnosis, demonstration of melanosomes, junctional complexes, cilia, etc | EM

Test DetailsA variety of clinical EM services are offered by the Electron Microscopy Facility which includes preparation of one micron thick toluidine blue stained plastic sections and ultrathin sections in anticipation of routine transmission electron microscopy. Digital images and expert diagnostic interpretation are provided by members of the Divisions of Anatomic and Molecular Pathology and Neuropathology in the Department of Pathology and Immunology.
MethodologyElectron microscopy
PerformedMonday – Friday
Turnaround3 – 4 business days
Sample CollectionExcise tissue in 1mmx1mm or less in 1 dimension. Use modified Karnovsky’s fixative in a 30:1 fixative to tissue ratio, contact lab directly for fixative information.
Minimum sample volumeMaximum1mm x 1mm in one dimension for whole tissue
Storage/Transport ConditionsRoom temperature in EM fixative
Unacceptable ConditionsWrong Fixative, delay after excision, tissue too large to penetrate
Special InstructionsAlways contact lab for sample preparation instructions and guidance prior to sample collection
CPT Code(s)88348