Ambiguous neoplasms: diagnosis, demonstration of melanosomes, junctional complexes, cilia, etc | EM
| Test Details | A variety of clinical EM services are offered by the Electron Microscopy Facility which includes preparation of one micron thick toluidine blue stained plastic sections and ultrathin sections in anticipation of routine transmission electron microscopy. Digital images and expert diagnostic interpretation are provided by members of the Divisions of Anatomic and Molecular Pathology and Neuropathology in the Department of Pathology and Immunology. |
| Methodology | Electron microscopy |
| Performed | Monday – Friday |
| Turnaround | 3 – 4 business days |
| Sample Collection | Excise tissue in 1mmx1mm or less in 1 dimension. Use modified Karnovsky’s fixative in a 30:1 fixative to tissue ratio, contact lab directly for fixative information. |
| Minimum sample volume | Maximum1mm x 1mm in one dimension for whole tissue |
| Storage/Transport Conditions | Room temperature in EM fixative |
| Unacceptable Conditions | Wrong Fixative, delay after excision, tissue too large to penetrate |
| Special Instructions | Always contact lab for sample preparation instructions and guidance prior to sample collection |
| CPT Code(s) | 88348 |