Products of conception chromosome analysis | Classical cytogenetics
| Test Details | Detects aneuploidy, rearrangements, deletions, inversions |
| Methodology | Chromosome analysis / karyotype |
| Performed | Monday – Saturday |
| Turnaround | 21 – 30 days |
| Specimen Requirements | Products of conception (POC) |
| Sample Collection | Skin: Collect 3-4mm_ skin biopsy (about the size of a pencil eraser) and place in 50ml tube with transport media (provided by the cytogenetics lab). Villi: Collect 1 cm_ placenta by sterile procedure, and place in 50ml tube with transport media (provided by the cytogenetics lab). |
| Storage/Transport Conditions | Refrigerate after collection |
| Unacceptable Conditions | Specimens in formalin (POC in sterile saline is acceptable) |
| Special Instructions | Refrigerate if sample cannot be delivered within 24 hours; Send to Clinical Support Office (509 S. Euclid Ave., Room 4711 between 8 a.m. and 5 p.m.) After hours, please send to IOH Core Lab (425 S. Euclid, Room 4701) Uniquely identify twins/multiples |
| CPT Code(s) | 88291×1, 88233×1, 88262×1, 88280×1 |