ChromoSeq®
| Test Details | ChromoSeq® is a whole genome sequencing assay intended for the comprehensive clinical genomic evaluation of known or suspected hematologic neoplasms including AML, MDS, and B-ALL. ChromoSeq® is capable of unbiased detection of chromosomal translocations, copy number alterations, single nucleotide variants, and insertions/deletions from DNA. The assay can also provide data in the setting of failed or incomplete cytogenetics. |
| Relevant Condition(s) | Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), B-Cell Acute Lymphoblastic Leukemia (B-ALL) |
| Methodology | Whole Genome Sequencing |
| Turnaround Time | Approximately 6 business days |
| Specimen Requirements | 1.0 mL peripheral blood or bone marrow aspirate collected within 14 days |
| Specimen Collection | K2 EDTA tube |
| Minimum Specimen Volume | 0.5 mL peripheral blood or bone marrow aspirate |
| Storage/Transport Conditions | Ship at room temperature within 72 hours of collection |
| Unacceptable Conditions | Fresh or FFPE tissue, incorrect specimen container, or unlabeled specimen |
| CPT Code(s) | 81479, G0452 (Professional interpretation) |