ALK_2p23 | FISH

Test DetailsNSCLC – Detects rearrangements at 2p23 and single red 3′ ALK (FFPE: IVD probe kit)
Anaplastic – Detects rearrangements at 2p23
Relevant Condition(s)NSCLC, Anaplastic
MethodologyFluorescence in-situ hybridization
PerformedMonday – Friday
Turnaround3 – 5 days; STAT FISH performed within 24 – 48 hours
Specimen RequirementsFFPE (NSCLC, Anaplastic)
(Anaplastic – also offered on Suspension FISH test menu on Bone marrow, Bone core, Lymph node or Peripheral Blood)
Sample CollectionFormalin-fixed paraffin embedded tissue samples
(3 unstained slides or block)
Minimum Sample VolumeNot applicable as long as tumor cells are present
Storage/Transport ConditionsRoom temperature
Unacceptable ConditionsTissue samples on un-charged microscope slides, previously stained slides (H&E, IHC, etc.)
Special InstructionsMust provide a marked H&E guide slide and a copy of the related pathology report.
Do not refrigerate if sample cannot be delivered within 24 hours;
Send to Clinical Support Office (509 S. Euclid Ave., Room 4711 between 8 a.m. and 5 p.m.)
After hours, please send to IOH Core Lab (425 S. Euclid, Room 4701)
LimitationsDecalcification reagents may adversely affect FISH results.
CPT Code(s)88377