Her2 (Her2-neu, ERBB2)

Test DetailsThis test was verified by AMP Core Labs as a predictive biomarker for breast carcinomas.
MethodologyImmunohistochemistry using Ventana PATHWAY anti-HER2/neu (clone 4B5)
PerformedMonday – Friday
Turnaround2 – 3 business days
Specimen RequirementsFor Ventana IHC, sections should be on Plus(+) charged slides.
Sample CollectionIt is important to indicate the collection time so total fixation time can be calculated. The total duration of formalin fixation should be in the range of 6-72 hours. Devitalization time is not required for core biopsies where specimens are always immediately transferred to formalin. Testing is not validated for decalcified specimens.
Storage/Transport ConditionsRoom temperature (use cold packs for transport of blocks during summer months)
CPT Code(s)88360 (with morphometric analysis) according to ASCO/CAP guidelines